Compare vacation rentals in Seneca, SC from 100+ sites!

This Seneca vacation rental is a 12-minute walk from the Shaver Recreation Complex and a 5-minute drive from Lake Keowee, offering easy access to outdoor recreation.
The 1400-square-foot apartment sleeps six guests and features three bedrooms, two bathrooms, a fully equipped kitchen with modern appliances, in-unit laundry, a private garden, and parking.

This one-bedroom loft apartment is located in historic downtown Seneca, offering convenient walkability to local shops and restaurants, and is a short drive to Lake Keowee and Clemson University. This accommodation comfortably sleeps up to 4 guests and includes a full kitchen, private bathroom, and an in-unit washer/dryer.

This unique tiny house lodging offers a secluded retreat in a tranquil wooded campground, providing a distinctive alternative to traditional hotel accommodations in Seneca.
This cozy dwelling accommodates up to 2 guests, features a full kitchen, air conditioning, and parking, and is ideal for travelers seeking a nature-focused getaway with a quiet, vintage campground atmosphere.

This Seneca waterfront cabin is located just a short distance from Lake Keowee, with popular attractions like Keowee Key Golf Course and Art Circle Gallery within a 12-mile radius. Guests consistently rate the cabin excellent for location, cleanliness, and overall experience. This 2300 square foot cabin comfortably accommodates up to 12 guests with four bedrooms and four bathrooms. Enjoy the spacious living areas, modern kitchen with dishwasher, and relaxing amenities like a jacuzzi, fireplace, and outdoor barbecue.

Hodge Island Cabin, near Clemson University, provides a peaceful wooded retreat close to hiking trails and fishing spots in Utica, South Carolina.
This one-bedroom, one-bathroom cabin sleeps two guests and features a fully equipped kitchen (fridge, microwave, dishwasher), air conditioning, a garden, parking, and a spacious deck; Clemson University game days are conveniently accessible.

This Walhalla rental property is located in a quiet neighborhood, 4 minutes from downtown Walhalla and the Performing Arts Center, 2 minutes from Sertoma Field (Oktoberfest site), 28 minutes from Clemson University, 18 minutes from Stumphouse Tunnel, 20 minutes from Oconee State Park, 15 minutes from Lake Keowee, 25 minutes from Lake Jocassee, and 28 minutes from Lake Hartwell.
This 3-bedroom, 2-bathroom apartment accommodates up to 6 guests and features air conditioning, a private master suite, a bonus room, a fully equipped kitchen with coffee makers, an air fryer, and a blender, a screened-in porch, and a backyard with a Blackstone grill and outdoor TV.

This Seneca, South Carolina cabin offers a secluded retreat amidst trees and open fields, providing stunning wildlife views.
The 2-bedroom, 2-bathroom house sleeps 4 guests and features a kitchen with a fridge, microwave, and dishwasher; a hot tub; a fireplace; and a fire pit, perfect for enjoying the outdoors.

This Seneca, South Carolina lakefront duplex, a 7-mile drive from Clemson University, offers easy access to both campus events and local attractions.
This fully renovated 2-bedroom, 2-bathroom unit features a new kitchen, granite and marble countertops, stainless steel appliances, a jacuzzi, parking, and accommodates up to 2 guests.

This Utica rental condo is located 15 to 40 minutes from Clemson University, Tri-County Tech, Anderson University, and downtown Seneca, offering a quiet setting with easy access to shopping and dining.
This 3-bedroom, 2-bathroom dwelling accommodates up to 7 guests with a fully equipped kitchen, dishwasher, air conditioning, and private parking, making it ideal for families or groups visiting local educational institutions.

This Seneca lake house, near Lake Keowee, is a 20-minute drive from Clemson University, offering easy access to both the university and local shops and restaurants.
This hand-built tiny home features a queen-size sofa bed, a loft with two single beds (or a king-size option), a full kitchen with a fridge, air conditioning, Wi-Fi, a private dock on Lake Keowee, and accommodates up to four guests.

This Seneca cottage is conveniently located minutes from downtown Seneca, 10 miles from Clemson University, and under an hour from Greenville, Highlands, and Cashiers, offering easy access to Cane Creek Landing and South Cove Park.
The one-bedroom, one-bathroom house features a queen bed, small kitchen, living room, dining area, washer/dryer, front and back porches with rocking chairs, and access to a fire pit, comfortably accommodating two guests and boasting beautiful sunrise views over Lake Keowee.

This Seneca, South Carolina vacation rental is located 10 miles from Clemson University and offers easy access to Lake Hartwell.
This three-bedroom, two-bathroom house sleeps six guests and features a fully equipped kitchen, in-unit laundry, a smart TV with Amazon Prime, a gas grill, a fire pit, and a spacious yard perfect for pets.