Vacation rentals in Clayton, MO

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Clayton, MO vacation rentals
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Best Vacation rentals and Airbnb offers in Clayton, MO

Browse Vacation Rentals in the Historic District of Clayton, MO

These central Clayton, MO vacation rentals make exploring downtown easy on foot. Skip the hassle of transfers and enjoy a convenient city stay.

Historic French Charm  Easy Walk To Italian Eats - Clayton, MO
9.8 717 reviews

Historic French Charm Easy Walk To Italian Eats

apartment, St Louis
This charming apartment is located in St. Louis' Southwest Garden district, just minutes from the zoo, Route 66, and downtown, making it a great base for exploring the city. The apartment has received excellent ratings for cleanliness, location, and user experience.
The apartment has one bedroom and one bathroom, accommodating up to four guests. It offers a range of amenities including a fully equipped kitchen, a cozy living area with a TV, and access to outdoor spaces with patio furniture.
Warriors Rest And Repose In St. Louis Hills - Clayton, MO
9.8 245 reviews

Warriors Rest And Repose In St. Louis Hills

apartment, St Louis
This first-floor apartment is conveniently located in the St. Louis Hills neighborhood, close to Chippewa and Hampton Avenues, offering easy access to both city parks and the River Des Peres Greenway Trail. The apartment consistently receives excellent ratings for its cleanliness, location, and overall experience. This one-bedroom, one-bathroom apartment comfortably accommodates two guests, with an open floor plan that creates a spacious and airy feel. The apartment offers modern amenities like a smart TV, Wi-Fi, and keypad locks for added security and convenience, along with a large grassy backyard, perfect for relaxing or enjoying the outdoors.
Bright 2nd-floor Flat On The Hill/sw Gardens Dist. - Clayton, MO
9.8 329 reviews

Bright 2nd-floor Flat On The Hill/sw Gardens Dist.

apartment, St Louis
This apartment is located in the Southwest Garden neighborhood of St. Louis, just a short distance from Tower Grove Park and other attractions. It’s rated excellent by previous guests. This one-bedroom rental has a comfortable 600 square feet of space and can accommodate up to four guests. The apartment includes a fully equipped kitchen, a private balcony, and access to a garden, spa, and tennis court.
Modern Studio Apartment In Central West End, Bj Hospital - Clayton, MO
9.4 13 reviews

Modern Studio Apartment In Central West End, Bj Hospital

studio, St Louis
This St. Louis apartment rental is in the Central West End, a 15-minute walk from Forest Park, the Cathedral Basilica of St. Louis, and Barnes-Jewish Hospital.
This 470-square-foot unit features one bedroom, one bathroom, sleeps two guests, and includes free WiFi, a Smart TV, and a fully equipped kitchen with parking.

Best Clayton, MO vacation rentals with air conditioning

Heart Of Springvale Shopping - Clayton, MO
No reviews

Heart Of Springvale Shopping

apartment, Springvale
This Springvale apartment offers prime access to the Springvale Shopping district, located 23 miles from Essendon Fields Airport.
This 1020 sq ft, one-bedroom unit accommodates up to 7 guests and features a private balcony, a fully equipped kitchenette, air conditioning, and on-site reception.
Hidden Gem In The  Of Stl - Clayton, MO
9.0 38 reviews

Hidden Gem In The Of Stl

apartment, St Louis
This St. Louis rental unit is located in the Northampton neighborhood, offering convenient access to downtown attractions like the Arch and Busch Stadium, just a short drive away, and is situated near major highways 64/40, 44, and I-55.
This 1190 sq ft, 3-bedroom, 1-bathroom apartment accommodates up to 6 guests and features a fully equipped kitchen, 1 GIG internet, air conditioning, a terrace, a shared backyard patio with grilling facilities, and parking, with a check-out time of 12:00 PM.
Modern First-floor 3br Near The Loop & Forest Park - Clayton, MO
9.9 330 reviews

Modern First-floor 3br Near The Loop & Forest Park

apartment, St Louis
This apartment is located in St. Louis, conveniently situated within a 15-minute walk of The Loop and Forest Park, offering easy access to some of the city's most popular attractions. Guests consistently rate this rental as excellent for its location, cleanliness, and overall experience.
This spacious 3-bedroom, 1-bathroom apartment spans 1190 square feet. Enjoy amenities like a swimming pool, jacuzzi, fitness center, tennis court, and a private yard, perfect for families and groups looking for a comfortable and enjoyable stay.
Comfie House Clayton - Clayton, MO
No reviews

Comfie House Clayton

apartment, Clayton South
This 4-bedroom, 4-bathroom apartment in Clayton South, Australia, is conveniently located just 0.2 miles from Monash University and Monash Hospital, with direct bus access and a 20-minute train ride to Melbourne CBD.
This rental offers accommodation for up to 5 guests, with internet, air conditioning, and driveway parking for one vehicle, providing a practical base for exploring local beaches and amenities.

Frequently Asked Questions about vacation rentals in Clayton, MO

  • Which neighborhood in Clayton, MO should you consider for a vacation rental?

    The Central West End is a great choice, with its proximity to Forest Park, the Saint Louis Zoo, and the Missouri History Museum. You'll also be within walking distance of great restaurants and shops.
  • What are the best Airbnb and vacation rentals in Clayton, MO?

  • What are the top family-friendly attractions in Clayton, MO?

    The Saint Louis Zoo is a must-visit for families, with its diverse animal collection and interactive exhibits. The Magic House is a great option for kids, with hands-on exhibits and play areas.
  • What are the most popular Airbnbs in Clayton, MO?

  • When is the best time to book a vacation rental in Clayton, MO?

    The best time to book a vacation rental in Clayton is during the shoulder seasons, from April to May or September to October, when the weather is pleasant and the crowds are smaller.
  • What are the best vacation rentals with a pool in Clayton, MO?

    The best vacation rental with a pool in Clayton, MO is King Bed - Comfy Environment - Cozy Space - Corporate Luxury.

  • What are the best budget-friendly activities in Clayton, MO?

    Take a walk or bike ride through Forest Park, it's a great way to enjoy the outdoors without spending any money. You can also visit the Missouri History Museum or the Saint Louis Art Museum, both of which offer free admission.
  • What are the best rentals for families and kids in Clayton, MO?

  • What are the best restaurants with local dishes in Clayton, MO?

    For authentic St. Louis-style barbecue, head to Pappy's Smokehouse. If you're looking for a more upscale dining experience, try The Capital Grille for prime steaks and seafood.
  • What are the best walking or cycling routes in Clayton, MO?

    The Loop Trail in Forest Park is a great option for both walking and biking. It's a 4.5-mile paved trail that winds through the park and offers scenic views.
  • Are there pet-friendly attractions in Clayton, MO?

    Yes, many attractions in Clayton are pet-friendly. Forest Park is a great place to take your dog for a walk, and many restaurants have outdoor seating where you can enjoy a meal with your furry friend.
  • What are the benefits of choosing a vacation rental in Clayton, MO?

    Vacation rentals offer more space and privacy than hotels, and they often come with amenities like kitchens and laundry facilities. They can also be a more affordable option, especially for families or groups.
  • What are the top sports attractions and facilities in Clayton, MO?

    Busch Stadium, home to the St. Louis Cardinals, is a major draw for baseball fans. The city also has a number of other sports facilities, including the Enterprise Center, home to the St. Louis Blues hockey team.

Popular destinations

Best Vacation Rentals with Balconies in Clayton, MO

Enjoy your own private terrace with city skyline views at these vacation rentals in Clayton, MO.

Chic 3br Gem | Tg Park | Patio+yard+w/d+workspace - Clayton, MO
10 2 reviews

Chic 3br Gem | Tg Park | Patio+yard+w/d+workspace

apartment, St Louis
This 3-bedroom flat in Tower Grove South is located between Tower Grove Park and the dining and entertainment areas of South Grand and Morganford, offering quick access to Busch Stadium (8 miles), the Gateway Arch (10 miles), Forest Park (8 miles), and the Botanical Gardens (6 miles).
This 1170 sq ft apartment accommodates up to 8 guests and features a designer kitchen with marble countertops, a workspace with high-speed internet, an in-unit washer/dryer, and a patio overlooking a fenced backyard.
Hill Retreat: Rustic Charm W/ Balcony - Clayton, MO
9.4 22 reviews

Hill Retreat: Rustic Charm W/ Balcony

apartment, St Louis
This 800-square-foot, two-bedroom apartment rental in St. Louis's The Hill neighborhood is conveniently located within four blocks of numerous Italian restaurants and cafes.
The unit features a full kitchen, a private balcony, and accommodates up to four guests with a queen bed and a sofa bed, plus a pet (for an additional $100 non-refundable fee).
South City Top Floor Apartment - Clayton, MO
9.3 80 reviews

South City Top Floor Apartment

apartment, St Louis
This charming apartment is located in South City, just a few blocks from the lively Cherokee Street district and within easy reach of St. Louis's top attractions. The apartment consistently receives excellent ratings for location, cleanliness, and user experience.
This comfortable rental features one bedroom and one bathroom, accommodating up to three guests. Enjoy amenities like a private office space, an updated kitchen, a porch, and a dog-friendly environment, making it perfect for both work and leisure.

Top Vacation Rentals for Families in Clayton, MO

These kid-friendly vacation rentals in Clayton, MO keep you close to top city attractions for a stress-free family vacation.

Central West End/washu/bjc/st Louis Children's Hospital/forest Park 3br Euphoria - Clayton, MO
9.0 9 reviews

Central West End/washu/bjc/st Louis Children's Hospital/forest Park 3br Euphoria

apartment, St Louis
This three-bedroom, two-bathroom St. Louis apartment is ideally located in the Central West End, two blocks from Barnes-Jewish Hospital and Washington University, providing easy access to Forest Park and other major attractions.
This spacious rental sleeps ten guests comfortably, boasting a king bed, two queen beds, two sleeper sofas, a jacuzzi tub, in-unit laundry, and free Wi-Fi, plus a well-equipped kitchen and dedicated workspace.
Park Avenue - Ikon Glen Waverley - Clayton, MO
8.3 663 reviews

Park Avenue - Ikon Glen Waverley

studio, Glen Waverley
Located just 2 minutes from Glen Waverley Station and The Glen Shopping Centre, this luxury 4.5-star aparthotel has a very good user rating and excellent location rating.
The modern and stylish apartments feature fully equipped kitchens, in-room laundry facilities, flat-screen TVs with cable channels, and limited housekeeping services. Guests can also enjoy a fitness center, restaurant, garden, and terrace/balcony.
Luxurious Oasis In Glen Waverley (Free Carpark) - Clayton, MO
9.9 23 reviews

Luxurious Oasis In Glen Waverley (Free Carpark)

apartment
This Glen Waverley apartment rental is ideally located one minute from The Glen shopping center and three minutes from Glen Waverley Station, offering easy access to shopping and public transportation.
This two-bedroom, two-bathroom unit sleeps six guests comfortably, featuring a queen bed, two single beds, a double sofa bed, a Smart TV, free Wi-Fi, secure parking, and a private balcony.
Modern 4br Retreat With Free Parking In Prime Cwe! - Clayton, MO
10 1 review

Modern 4br Retreat With Free Parking In Prime Cwe!

house, St Louis
This modern four-bedroom home is ideally located in St. Louis's Central West End, a mile from the Fox Theatre, 2.3 miles from Forest Park, and 3.6 miles from the St. Louis Zoo.
This 1980-square-foot house comfortably sleeps 15 guests and features three bathrooms, a fully equipped kitchen with a dishwasher, free Wi-Fi, and free on-site parking.

Best Clayton, MO vacation rentals with parking

Cozy House On The Hill - Clayton, MO
9.7 370 reviews

Cozy House On The Hill

apartment, St Louis
Mount Waverley Townhouses - Clayton, MO
8.1 123 reviews

Mount Waverley Townhouses

apartment, Mount Waverley
Charming 1-bedroom Top Unit House In Central Dog Town - Clayton, MO
10 3 reviews

Charming 1-bedroom Top Unit House In Central Dog Town

apartment, St Louis
Comfy Studio Close To Monash Uni - Clayton, MO
9.8 51 reviews

Comfy Studio Close To Monash Uni

apartment

Compare Luxury Vacation Rentals in Clayton, MO

Elevate your travel experience with a luxury rental in Clayton, MO, where high-end design meets a prime location.

Tranquil Home With Big Tv And Fast Internet - Clayton, MO
No reviews

Tranquil Home With Big Tv And Fast Internet

apartment, Glen Waverley

Our Favorite Pet-Friendly Vacation Rentals in Clayton, MO

Stay in a pet-friendly vacation rental in Clayton, MO situated near dog parks and city walks, ensuring a comfortable stay for both you and your pet.

Domi Rentals - The Blackburn Residences - Clayton, MO
9.6 14 reviews

Domi Rentals - The Blackburn Residences

house, Notting Hill
Charming 2-bedroom, Cozy Bungalow With Sunroom In Fabulous St. Louis With Wifi - Clayton, MO
9.0 34 reviews

Charming 2-bedroom, Cozy Bungalow With Sunroom In Fabulous St. Louis With Wifi

apartment, St Louis
Stylish Family Home With A Fully Fenced Yard - Clayton, MO
10 41 reviews

Stylish Family Home With A Fully Fenced Yard

apartment, St Louis
Dog-friendly South City 1st Floor Apartment - Clayton, MO
9.5 147 reviews

Dog-friendly South City 1st Floor Apartment

apartment, St Louis

Explore Vacation Rentals with a Pool in Clayton, MO

Dive into a refreshing stay with these Clayton, MO rentals and Airbnbs that offer on-site swimming pool access in the heart of the city.

Cathedral Basilica Of Saint Louis Tour! Pets Allowed! W/ Parking, Pool & Cinema! - Clayton, MO
No reviews

Cathedral Basilica Of Saint Louis Tour! Pets Allowed! W/ Parking, Pool & Cinema!

apartment, St Louis
Contemporary Hotel In Central West End District! 3 Spacious Spaces Parking, Pool - Clayton, MO
No reviews

Contemporary Hotel In Central West End District! 3 Spacious Spaces Parking, Pool

apartment, St Louis
Close To Missouri History Museum! Pets Allowed! Parking, Pool, And Cinema! - Clayton, MO
8.0 1 review

Close To Missouri History Museum! Pets Allowed! Parking, Pool, And Cinema!

apartment, St Louis
Lovely 1 Bedroom Apt At M-city, Awesome Amenities! - Clayton, MO
9.7 39 reviews

Lovely 1 Bedroom Apt At M-city, Awesome Amenities!

apartment, Clayton

Search Vacation Rentals with Jacuzzi in Clayton, MO

Unwind at the end of a busy city day with a private hot tub at these hand-selected vacation rentals in Clayton, MO.

3-bedroom Apartment In Charming St. Louis With Close To Many Attractive Places. - Clayton, MO
8.0 1 review

3-bedroom Apartment In Charming St. Louis With Close To Many Attractive Places.

apartment, St Louis
Charming Stl Brick W/ Firepit-  Kingbed- 5min Botanical Garden - Clayton, MO
9.4 3 reviews

Charming Stl Brick W/ Firepit- Kingbed- 5min Botanical Garden

apartment, St Louis
Casa Esma On The Hill - Luxury Couples Retreat W/ Private Hot Tub - Clayton, MO
10 1 review

Casa Esma On The Hill - Luxury Couples Retreat W/ Private Hot Tub

apartment, St Louis
Ultimate Group Manor: Cold Plunge + Arcade + Sauna - Clayton, MO
10 1 review

Ultimate Group Manor: Cold Plunge + Arcade + Sauna

apartment, St Louis
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